### Diagnosis Inflammation of the liver. ### Epidemiologic Risks Depends on the etiology, many infections can involve the liver, the main ones being viral. ### Microbiology *[[Brucella]]*, [[Cytomegalovirus]], [[Epstein-Barr Virus]], [[Hepatitis A]], [[Hepatitis B]], [[Hepatitis C]], [[Hepatitis D]], [[Hepatitis E]], [[Herpes]] simplex virus, *[[Leptospira]]*, [[Lyme]] disease, Q Fever (*[[Coxiella]]* *burnetii*), syphilis (*[[Treponema]]* *pallidum*) (especially in [[HIV]]), [[Yellow Fever]] at a minimum, the number of infections that can acutely involve the liver is, well, all of them. Just about. ### Empiric Therapy It depends on the infection. ### Pearls In [[HIV]] patients with unexplained increased ALT, chronic [[Hepatitis E]] was found in 2.6%, so it wasn't so unexplained, was it? ### Rants Do not forget your damn [[Vaccine]]. Have you had your A? Your B? No? More the fool you.