### Microbiology A mold. *A. kalrae* (most reported human cases), *A*. *alba*, *A*. *cuboidea*, and *A*. *longicola*, and others. It is hard out there for a mold. *[[Arthrographis]]* "produce only poorly differentiated arthroconidial asexual morphs in culture." [^2] Sounds like a Portland bar. ### Epidemiologic Risks The mold is ubiquitous, especially in rotting organic material. ### Syndromes A hodgepodge of infections, many after penetrating environmental injuries and in those with bad immune systems. The Pubmeds reveal only 16 hits and one each for a hodgepodge of infections. ### Treatment Azoles, especially [[Posaconazole]], and [[Terbinafine]]. NOT [[Amphotericin B]] or echinocandins . ### Notes And how often do you find a *Fungus of the Month* in *Fine Wood Working*? You can *Spalt Your Own Lumber with [[Arthrographis]] cuboidea*. [^1] > [[Arthrographis]] cuboidea is responsible for most of the cotton candy pink stains you see in lumber of hardwoods. Spalt just sounds wrong, the past tense of some questionable Teutonic practice. Although *A. cuboidea* is not a human pathogen, it can turn your workshop pink. ### Puswhisperers [Medical Spalt](http://pusware.com/PW7/MedicalSpalt.html) [Audio. The Gobbet 'o Pus Podcast](http://www.pusware.com/gobbet/gop922.mp3) ### Rationalizations [^1]: https://www.finewoodworking.com/2010/05/01/spalt-your-own-lumber-fungus-of-the-month-arthrographis-cuboidea [^2]: Mycoses. 2014 Apr;57(4):247–8. doi: 10.1111/myc.12151. Epub 2013 Oct 22. In vitro antifungal susceptibility of clinical isolates of [[Arthrographis]] kalrae, a poorly known opportunistic fungus. My one case was an elderly male with long-standing inflammatory [[arthritis]] on low dose prednisone and weekly methotrexate.