# Phenopackets — GA4GH Phenopacket Schema ## Overview The GA4GH Phenopacket Schema is a community standard for the computable exchange of clinical and phenotypic data linked to genomic information. It captures a patient's phenotypic features using [[HPO]] terms, diagnoses, biosample data, genomic variants via [[VCF]] or [[VRS]], medical actions, and pedigree information in a single structured package. It supports rare disease, complex disease, and cancer use cases, and is interoperable with [[HL7 FHIR]] via a published implementation guide. ## Connections - Governed by: [[GA4GH]] (Clinical and Phenotypic Data Capture Work Stream) - ISO standard: ISO/TS 5435 (2022) - Uses: [[HPO]], [[VCF]], [[VRS]] - Implements: [[HL7 FHIR]] (published FHIR implementation guide) ## Resources - https://www.ga4gh.org/product/phenopackets/ - https://phenopacket-schema.readthedocs.io - https://github.com/phenopackets/phenopacket-schema