# tRNA --- **Transfer RNA**, or "tRNA" is a class of [[RNA]] that transfers [[amino acid.png|amino acids]] to the growing protein during [[translation]]. Each tRNA has it's own [[codon#Anticodon|anticodon]] and the amino acid that corresponds to it. In other words, they allo amino acids to interact with an mRNA template. ## Structure The structure of a tRNA is a sort of cross-shape bent into an L. One end has an [[codon#Anticodon|anticodon]] on one end and the amino acid on the other. ![[tRNA.png]] ## Translation tRNA is essential during the process of [[translation|translation]], by bringing amino acids to the [[ribosome]]. ![[translation.png]] An input of energy from [[adenosine triphosphate]] is required to attach an amino acid to a tRNA, and the enzyme that "reloads" the aminos acid is called "aminoacytl-tRNA synthetase". ### tRNA in the Ribosome tRNA enters the [[ribosome]] at the [[ribosome#A P and E Sites|A site]] ## Wobble Pairing **Wobble pairing** allows one tRNA to bind to multiple different codons. It the first two bases of the [[codon]] and [[codon#Anticodon|anticodon]] match, then the third base can form bond that does not conform to the usual [[complementary base pairing]]. First, the first two bases pair up, then the tRNA flexes, or "wobbles" to fit the third one. Important distinction: Wobble pairing explains only how one tRNA can read more than one codon, not how one amino acid can be specified by more than one codon. ___