# Prokaryote
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**Prokaryotes** are organisms that are classified in the [[domains of life|domains]] [[bacteria]] and [[archaea]]. These organisms are pretty small—for example, a bacteria is about the size of a eukaryote's mitochondria.
Not to be confused with [[microbe|microbes]], as there are microbes that are actually eurkaryotes, and viruses also can count as a microbe, even though they aren't prokaryotes or eukaryotes.
## Features of All Prokaryotes
The features of prokaryotes that are common across the two domains are these:
- lack a discrete, membrane-bound [[nucleus|nucleus]], instead they have their chromosomal DNA "nucleoid" region.
- have [[prokaryotic DNA|DNA]]
- have [[cytoplasm]]
- have [[ribosome|ribosomes]]
- have a [[cytoskeleton]]
- have a [[plasma membrane|cytoplasmic membrane]]
- have a [[cell wall]]
## Features of Only Some Prokaryotes
Some features are found in some but not all prokaryotes.
- [[plasmid]] DNA
- [[flagella]]
- [[pili]]
- [[capsule]]
- [[endospore|endospores]]
## Differences Between Bacteria and Archaea
Despite looking very similar to each other from a certain perspective, there are actually many important **disctinctions** between archaea and bacteria.
- Bacteria and archaea have very different **[[tRNA]] sequences**.
- Bacteria and archaea have very different **[[DNA]] sequences**.
- There are clear differences in the **[[cell wall]]** and **[[plasma membrane|cell membrane]]** make up between bacteria and archaea.
Additionally, archaea tend to live in extreme environments.
## History
Most of life's history is prokayrotic, from 3.6 billion years ago to 1.8 billion years ago, it was all prokaryotes. "Cyanobacteria" started making a lot of oxygen, which is *essential* for the devolopment of eukaryotes.
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