# Nitrates --- **Nitrates** are a class of [[medicine]] that used to treat heart conditions such as [[angina]] and [[myocardial infarction]]. ## Mechanism of Action Nitrates are a potent vasodilaton, which smoothens the smooth muscle of the arteries. ## Adverse Ractions - significant drops in [[blood pressure]] - makes you very dizzy - killer headache (not literally) ## Meds - **Nitroglycerine** (NTG) - can be taken sublingually or as a paste or patch - short term management for [[angina]] - if administering to someone else, *wear gloves* because it *will* soak through your skin - can also be given IV - this is the only form safe for children - Isosorbide - for long-term management for [[angina]] ___