# Lactate
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**Lactate**, or **lactic acid** is a byproduct of created when [[pyruvate]] is used as a final electron acceptor during [[fermentation]]. In muscles it is a normal product of [[glycolysis]] even when resting.
Lactate is a good indicator for [[shock]] as it indicates that there is an abnormal amount of anaerobic respiration occurring due to a lack of profusion.
>[!science] Normal value
>The normal values for lactate are between **0.5-2.2** mEq/L for venous blood and **0.5 to 1.6** mmol/L for arterial blood.
![[lactic acid fermentation.png]]
In humans some of our cells (like those in [[skeletal muscle]] lack oxygen to fuel the [[ETC (mitochondria)|ETC]], they switch to [[fermentation#Types of Fermentation|lactic acid anaerobic respiration]]. It's not as efficient but it keeps the cells alive until there is oxygen again. During intense exercise, lactate can build up in the [[muscle tissue]] as the waste product of so much anaerobic respiration. The lactate travels to the blood where it ends up in the [[liver]] where can be reconverted back to [[pyruvate]] and then back to [[gluconeogenesis|glucose]].
![[lactate and glucose.png]]
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