up:: [[Dopamine]] Tags:: # Two pathways of dopamine in the brain Dopamine comes primarily from neurons in two pathways: ==1. Mesolimbic pathway 2. Mesostriatal pathway ![[Pasted image 20220912101852.png]]== ### Two Pathways The ==Mesostriatal== dopamine pathway involves the substantia nigra and striatum. This is why this pathway deals mostly with ==movement==. The ==Mesolimbic== dopamine pathway deals primarily with the VTA, nucleus accumbens, cortex, and hippocampus. This is why it makes you want to pursue things outside yourself. It deals with ==motivation, reward, reinforcement, and craving.== Related: Created: [[27-09-2022]] ___ # Resources The Neuroscience Textbook